To acknowledge please use this reference:

M.K. Levin, M.M. Hingorani, R.M. Holmes, S.S. Patel, J.H. Carson (2009) "Model-based global analysis of heterogeneous experimental data using " Methods Mol. Biol. 500:335-59

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Published applications of

Energy efficient translocation of hepatitis C virus NS3-4A helicase on single stranded RNA

Reference: V. Rajagopal, M. Gurjar, M.K. Levin, S.S. Patel (2010) J. Biol. Chem. 285
Data: Download three datasets presented in the paper [zip]
Model: Latest version of the model is located [here]

Experimental and computational analysis of DNA unwinding and polymerization kinetics

Reference: M. Pandey, M.K. Levin, S.S. Patel (2010) Methods Mol. Biol. 587:57-83
Model: Latest version of the model is located [here]

Mechanism of cadmium-mediated inhibition of Msh2-Msh6 function in DNA mismatch repair

Reference: M. Wieland, M.K Levin, K.S. Hingorani, F.N. Biro, M.M. Hingorani (2009) Biochem. 48(40):9492-9502
Data: Download the dataset presented in the paper [gfd]
Model: Latest version of the model is located here

Mechanism of ATP-driven PCNA clamp loading by S. cerevisiae RFC

Reference: S. Chen, M.K. Levin, M. Sakato, Y. Zhou, M.M. Hingorani (2009) J.Mol.Biol. 388(3):431-42
Data: Download the datasets presented in the paper [zip]
Model: Latest version of the model is located here

Model-based global analysis of heterogeneous experimental data using

Reference: M.K. Levin, M.M. Hingorani, R.M. Holmes, S.S. Patel, J.H. Carson (2009) Methods Mol. Biol. 500:335-59 [publisher's info]
Data: Download archive with models and data used in the chapter [zip]
Model: Latest versions of the models are located here [binding_eq_simple] [lattice_binding] [clamp_loader]

Significant proportions of nuclear transport proteins with reduced intracellular mobilities resolved by fluorescence correlation spectroscopy

Reference: A. Paradise, M.K. Levin, G. Korza, J.H. Carson (2007) J.Mol.Biol. 365(1):50-65
Model: [fcs_acf3D]

DNA synthesis by a polymerase provides a driving force to increase DNA unwinding by a helicase

Reference: N.M. Stano, Y.-J. Jeong, I. Donmez, P. Tummalapalli, M.K. Levin, S.S. Patel (2005) Nature 435(7040):370-3
Model: [unwinding]

Transient state kinetics of transcription elongation by T7 RNA polymerase

Reference: V.S. Anand, S.S. Patel (2006) J.Biol.Chem. 281. 35677–35685
Model: [polymerization]

The DNA unwinding mechanism of the ring helicase of bacteriophage T7

Reference: Y.-J. Jeong, M.K. Levin, S.S. Patel (2004) Proc.Natl.Acad.Sci.USA 101(19):7264-9
Model: [unwinding]

The functional interaction of the hepatitis C virus helicase molecules is responsible for unwinding processivity

Reference: M.K. Levin, Y.-H. Wang, S.S. Patel (2004) J.Biol.Chem. 279(25):26005-12
Model:

The +2 NTP binding drives open complex formation in T7 RNA polymerase

Reference: N.M. Stano, M.K. Levin, S.S. Patel (2002) J.Biol.Chem. 277(40):37292-300
Model:

Helicase from hepatitis C virus: energetics of DNA binding

Reference: M.K. Levin, S.S. Patel (2002) J.Biol.Chem. 277(33):29377-85
Data: to download right-click the link and select Save Link As... [txt]
Model: [lattice_binding]

Transient-state kinetics and computational analysis of transcription initiation

Reference: S.S. Patel, R.P. Bandwar, M.K. Levin (2002) in The practical approach series/Kinetic analysis of macromolecules, K.A. Johnson, ed., Oxford University Press
Model:
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